Which of the following is an example of an osmotic diuretic?

Mannitol is classified as an osmotic diuretic, which helps to manage fluid retention and promote urine output. It works primarily by increasing the osmolarity of the blood and renal tubular fluid, effectively drawing water into the renal tubules and preventing its reabsorption. This mechanism leads to an increased volume of urine produced, making it particularly useful in conditions such as acute renal failure, increased intracranial pressure, and certain types of glaucoma.

In contrast, furosemide, hydrochlorothiazide, and spironolactone belong to different classes of diuretics. Furosemide is a loop diuretic that inhibits sodium and chloride reabsorption in the loop of Henle, while hydrochlorothiazide is a thiazide diuretic that acts on the distal convoluted tubule to inhibit sodium reabsorption. Spironolactone is a potassium-sparing diuretic that works by antagonizing aldosterone in the collecting ducts. Each of these diuretics has a different mechanism of action and specific clinical uses, but none function as osmotic diuretics like mannitol does.