When administering mannitol, what must the nurse ensure about the solution?

Mannitol, an osmotic diuretic, must be filter-sterilized to ensure it is free from particulate matter and microbial contamination. This is crucial because any impurities can lead to serious complications, especially when administered intravenously. The filter sterilization process helps to maintain the safety and effectiveness of the medication by ensuring that only the sterile solution is administered to the patient.

Mannitol can crystallize at lower temperatures, and any visible particulates could cause embolism or other adverse effects upon infusion. Therefore, ensuring the solution is clear and sterile before administration is vital for patient safety.

In clinical practice, it’s common to observe mannitol solutions for clarity and to use appropriate filters during preparation and administration to prevent any particles from entering the bloodstream.