What is the risk associated with rapid intravenous administration of furosemide?

Rapid intravenous administration of furosemide is associated with the risk of auditory toxicity, particularly ototoxicity, which can lead to hearing loss and tinnitus. This risk becomes more pronounced when furosemide is administered quickly or in high doses. The mechanism behind this effect is related to the drug's impact on the inner ear's fluid balance, potentially disrupting the homeostasis of the auditory system.

While electrolyte imbalances, severe hypotension, and heart arrhythmias can occur with furosemide use, these issues are more related to its diuretic action and the resultant fluid and electrolyte shifts that occur over time, rather than the direct effects of a rapid infusion. Following the correct infusion protocol can help mitigate these risks. However, the specific concern of auditory toxicity is unique to aggressive or rapid administration, making it the correct answer in this context.