Name a contraindication for using acetazolamide.

Study for the Pharmacology Diuretic Agents Test. Use flashcards and multiple choice questions, each question comes with hints and explanations. Get ready for your exam!

Acetazolamide is a carbonic anhydrase inhibitor that can be used as a diuretic, but it is contraindicated in individuals who have a hypersensitivity to sulfonamides. This is crucial because acetazolamide shares a similar sulfonamide structure, which poses a risk for allergic reactions in those who are sensitive to this class of drugs. Patients with a known sulfonamide allergy may experience serious adverse reactions such as skin rashes, fever, and anaphylaxis if acetazolamide is administered.

The other scenarios mentioned, such as electrolyte imbalance, chronic kidney disease, and hypertension, do present concerns that may require careful management or dose adjustments, but they are not absolute contraindications to the use of acetazolamide. Instead, the presence of a sulfonamide allergy distinctly indicates that the drug should not be used due to the risk of an allergic reaction.

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