A client on hydrochlorothiazide reports feeling weaker. What should the nurse consider as a potential cause?

When a client experiences weakness while on hydrochlorothiazide, hypokalemia should be considered as a potential cause. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by the kidneys; however, it can also lead to the loss of potassium. When potassium levels drop (hypokalemia), patients may present with symptoms like muscle weakness, fatigue, and cramping due to its crucial role in muscle function and overall cellular activity.

Monitoring potassium levels is essential in patients taking thiazide diuretics, as inadequate potassium can significantly impact neuromuscular function. Additionally, addressing potassium levels can help mitigate any risks associated with muscle weakness and other complications such as arrhythmias, which can occur if hypokalemia is significant. Therefore, in this context, considering hypokalemia as a cause of the client's reported weakness is appropriate and highlights the need for vigilant management of electrolyte levels in patients on hydrochlorothiazide therapy.